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In 1559, Francisco Hernndez de Toledo, Spanish chronicler of the Indies, was the first European to bring tobacco seeds to the Old World, following orders of King Philip II of Spain

Journal of Clinical Oncology, 21(2):327-333

"At the end of the day, the ambition we have is to replace cigarettes as soon as possible, with better alternatives for the people who continue smoking." In a report published March 2018, British government agency Public Health England (PHE) found that while heated tobacco products are likely to have lower levels of harmful compounds compared to cigarette smoke, the "limited evidence" currently available suggests that are more harmful than e-cigarettes

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